British Air Force Typhoon FGR4s have conducted a mission with France's air force in a coordinated attack targeting an hidden munitions depot in Syria used by the IS group, according to the UK's MoD.
The site, identified by surveillance, was believed to be housing weapons and explosive materials, the announcement noted, and was situated in hills just north of Palmyra in the heart of Syria.
"The RAF jets used laser-guided Paveway IV weapons to target a several entry passages leading to the site... early reports are that the target was engaged successfully," officials stated.
There was no indication of any civilian impact in the attack on Saturday evening and all the aircraft made a safe return, the defence officials confirmed.
The British jets were backed up by a Voyager aerial refuelling aircraft.
The Islamic State group - alternatively referred to as the so-called Islamic State - imposed militant control over large swathes of Syria and Iraq before its territorial defeat in 2019.
"This action underscores British leadership, and resolve to work closely with allied nations, to eradicate any resurgence of IS and their harmful and extremist ideologies in the area," the British Defence Secretary the Defence Secretary remarked.
RAF aircraft have carried out surveillance missions over Syrian airspace to "deter any attempted resurgence" of the group after its defeat at the battle of Baghuz in 2019, the authorities noted.
"I must thank the personnel of our armed forces involved in this strike for their professionalism and their bravery," Healey added. "They were part of thousands of British troops stationed over the festive period. This operation, to eliminate dangerous terrorists who pose a risk to our safety, shows how our armed forces are ready to step up, throughout the year, ensuring Britain's security domestically and strong abroad."
During December, the US military carried out what it termed a "massive strike" on Daesh sites in Syria, subsequent to an assault claimed the lives of two US troops and a civilian interpreter in the Palmyra area.
The United Nations estimates IS still boasts between 5,000 and 7,000 fighters in Syria and Iraq.